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. 2018 Jul 24;18(3):3229–3241. doi: 10.3892/mmr.2018.9310

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Copyright: © Wu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 10. — Effect of fermented CS on the myocardial cAMP contents and the activities of serum PDEs in DOX-treated rats. (A) Myocardial cAMP contents and (B) the activities of PDEs in the cardiac tissue of rats treated with DOX alone, or in combination with 0.05 g/kg captopril, or with 0.75, 1.5 or 3 g/kg CS. Data are presented as the mean ± standard deviation. ^##P<0.01 vs. the normal control group; **P<0.01 vs. the DOX control group. CS, Cordyceps sinensis; DOX, doxorubicin; cAMP, cyclic adenosine monophosphate; PDEs, phosphodiesterases.