Table II.

Analysis of variance of a values between the two groups (n=30).

						P-value
Group	Pre-treatment	1 week	2 weeks	4 weeks	8 weeks	Group	Time	Group × time
Treatment	13.97±2.45	13.12±2.29a	11.67±1.95a,b	10.37±1.71a–c	9.11±1.96a–d	0.002	<0.001	<0.001
Control	14.38±2.23	13.85±2.1a	13.14±1.95a,b	12.52±2.03a–c	12.09±1.88a–d	–	<0.001	–
t-value	−0.681	−1.293	−2.919	−4.436	−6.000	–	–	–
P-value	0.499	0.201	0.005	<0.001	<0.001	–	–	–

The a value represents the balance from red to green, within the range +60 to −60.

^aP<0.05 vs. pre-treatment

^bP<0.05 vs. 1 week post-treatment

^cP<0.05 vs. 2 weeks post-treatment

^dP<0.05 vs. 4 weeks post-treatment.