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. 2018 Jun 29;18(3):2531–2540. doi: 10.3892/mmr.2018.9233

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Copyright: © Chen et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — Cell migration and invasion assay. The effects of CUL4A overexpression and CUL4A knockdown on (A) cell migration and (B) invasion ability in HEPG2 and MHCC97-H liver cancer cells. (C) Western blot analysis of key proteins expressed during epithelial-mesenchymal transition in HEPG2 liver cancer cells. Similar results were obtained in three independent experiments under a light microscope (magnification, ×100). Results are presented as the mean ± standard error of the mean. *P<0.05 vs. control group. CUL4A, cullin 4A; siRNA, small interfering RNA; Cldn3, claudin 3; Ocln, occludin; Epcam, epithelial cell adhesion molecule.