Table 3.

Association of cumulative systolic BP with 3D LA structure and function

	Cumulative systolic blood pressure
	Model 1		Model 2		Model 3
	β	P-value	β	P-value	β	P-value
3D LA Vmax (mL)	3.39	<0.001	2.86	<0.001	1.74	0.004
3D LA Vmin (mL)	1.39	<0.001	1.19	0.001	0.76	0.04
3D LA VpreA (mL)a	3.26	<0.001	2.91	<0.001	1.87	<0.001
3D LA total EV (mL)	1.99	<0.001	1.66	<0.001	0.98	0.006
3D LA passive EV (mL)	0.28	0.27	0.08	0.78	−0.10	0.72
3D LA active EV (mL)a	1.80	<0.001	1.65	<0.001	1.12	<0.001
3D LA LSmax (%)	−0.58	0.03	−0.28	0.35	−0.24	0.45
3D LA LSRe (s−1)	0.06	<0.001	0.06	0.006	0.05	0.02
3D LA LSRa (s−1)	−0.04	0.05	−0.04	0.06	−0.04	0.06

The multivariable linear regression model is showing coefficients per 300 mmHg-years for cumulative SBP and P-values.

Model 1: unadjusted; Model 2: model 1 + adjusted for age, sex, and race at year 30 examination; Model 3: model 2 + adjusted for physical activity, heart rate, educational level, body mass index, alcohol intake, diabetes, smoke, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol at year 30 examination.

3D, three-dimension; DBP, diastolic blood pressure; EV, emptying volume; LA, left atrium; LSmax, global longitudinal strain; LASra, second negative diastolic peak strain rate; LASre, first negative diastolic peak strain rate; SBP, systolic blood pressure; Vmax, maximum volume; Vmin, minimum volume; VpreA, preatrial contraction volume.

^aRace-specific statistically significant interactions.