Table 4.
Association of cumulative diastolic BP with 3D LA structure and function
| Cumulative diastolic blood pressure |
||||||
|---|---|---|---|---|---|---|
| Model 1 |
Model 2 |
Model 3 |
||||
| β | P-value | β | P-value | β | P-value | |
| 3D LA Vmax (mL) | 1.90 | <0.001 | 1.44 | 0.004 | 0.26 | 0.60 |
| 3D LA Vmin (mL) | 0.62 | 0.03 | 0.47 | 0.11 | 0.004 | 0.99 |
| 3D LA VpreA (mL) | 2.07 | <0.001 | 1.75 | <0.001 | 0.66 | 0.11 |
| 3D LA total EV (mL) | 1.27 | <0.001 | 0.97 | 0.001 | 0.26 | 0.38 |
| 3D LA passive EV (mL) | −0.06 | 0.77 | −0.22 | 0.34 | −0.39 | 0.10 |
| 3D LA active EV (mL) | 1.40 | <0.001 | 1.24 | <0.001 | 0.66 | 0.002 |
| 3D LA LSmax (%) | −0.41 | 0.07 | −0.29 | 0.22 | −0.23 | 0.37 |
| 3D LA LSRe (s−1) | 0.06 | <0.001 | 0.05 | 0.001 | 0.05 | 0.004 |
| 3D LA LSRa (s−1) | −0.04 | 0.008 | −0.04 | 0.02 | −0.03 | 0.05 |
The multivariable linear regression model is showing coefficients per 200 mmHg-years for cumulative DBP and P-values.
Model 1: unadjusted; Model 2: model 1 + adjusted for age, sex, and race at year 30 examination; Model 3: model 2 + adjusted for physical activity, heart rate, educational level, body mass index, alcohol intake, diabetes, smoke, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol at year 30 examination.
3D, three-dimension; DBP, diastolic blood pressure; EV, emptying volume; LA, left atrium; LASra, second negative diastolic peak strain rate; LASre, first negative diastolic peak strain rate; LSmax, global longitudinal strain; SBP, systolic blood pressure; Vmax, maximum volume; Vmin, minimum volume; VpreA, preatrial contraction volume.