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. 2018 Aug 20;18:837. doi: 10.1186/s12885-018-4731-9

Table 4.

Comparison of clinicopathological parameters of 97 locally advanced esophageal squamous cell carcinoma patients who received curative concurrent chemoradiotherapy according to VEGF day 28 level

Characteristics VEGF < 80 pg/mL group (N = 29) VEGF > 80 pg/mL group (N = 68) P value
Age
  < 60 years 21 (72%) 43 (63%) 0.38
  ≥ 60 years 8 (28%) 25 (37%)
T status
 1 + 2 8 (28%) 7 (10%) 0.031a
 3 + 4 21 (72%) 61 (90%)
N status
 0 + 1 9 (31%) 22 (32%) 0.90
 2 + 3 20 (69%) 46 (68%)
Stage
 II + IIIA + IIIB 11 (38%) 21 (31%) 0.50
 IIIC 18 (62%) 47 (69%)
Grade
 1 + 2 22 (76%) 49 (72%) 0.70
 3 7 (24%) 19 (28%)
Location
 Upper 14 (48%) 26 (38%) 0.36
 Middle + Lower 15 (52%) 42 (62%)

VEGF vascular endothelial growth factor

aStatistically significant