Fig. 1.
Treatment protocol and quantitative drug efficacy. Treatment protocol. G1: untreated control (n = 7); G2: treated with doxorubicin (DOX) (3 mg/kg, i.v., weekly, 2 weeks, n = 7); Group 3, treated with trabectedin (TRAB) (0.15 mg/kg, i.v., weekly, 2 weeks, n = 7). All treated mice were sacrificed on termination day-15, and tumors were resected for further histological evaluation