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. 2018 Aug 20;15:57. doi: 10.1186/s12977-018-0441-2

Table 4.

Characterization of LTR binding sites critical for 3q12.3 and 11p15.4 promoter activity in tumorigenic cells

Provirus Binding site LTR Binding site allele frequency Binding site evolution
3q12.3 HOX-PBX 5′ LTR 99.68% (fixed) Acquired
RFX3 5′ and 3′ LTR 99.96% (fixed) Present at the time of insertion
11p15.4 ATF 5′ LTR 99.88% (fixed) Acquired
RORA 5′ LTR 50.76% (polymorphic) Acquired