Table 1.
Complete list of statistically significant, differentially expressed miRNAs. Fold-change and direction of regulation refer to the CMT group versus the CMEC group expression
| miR | Gene ID | Fold-change | Regulation | p-value | p-value (corrected) |
|---|---|---|---|---|---|
| miR-9 | MI0008125_1 | 33.36 | up | 0.00E + 00 | 0.00E + 00 |
| miR-9 | MI0008081_1 | 33.36 | up | 0.00E + 00 | 0.00E + 00 |
| miR-9 | MI0008086_1 | 33.36 | up | 0.00E + 00 | 0.00E + 00 |
| miR-122 | MI0008015_1 | 24.08 | up | 0.00E + 00 | 0.00E + 00 |
| miR-183 | MI0008017_1 | 23.75 | up | 0.00E + 00 | 0.00E + 00 |
| miR-182 | MI0010336_1 | 18.90 | up | 0.00E + 00 | 0.00E + 00 |
| miR-106b | MI0008109_1 | 14.72 | up | 0.00E + 00 | 0.00E + 00 |
| mIR-31 | MI0007994_1 | 14.32 | up | 0.00E + 00 | 0.00E + 00 |
| miR-429 | MI0001644_1 | 12.47 | up | 0.00E + 00 | 0.00E + 00 |
| miR-203 | MI0010363_1 | 11.79 | up | 0.00E + 00 | 0.00E + 00 |
| miR-18a | MI0010324_1 | 10.34 | up | 0.00E + 00 | 0.00E + 00 |
| miR-146a | MI0008094_1 | 10.13 | up | 0.00E + 00 | 0.00E + 00 |
| miR-181c | MI0008034_1 | 9.99 | up | 0.00E + 00 | 0.00E + 00 |
| miR-96 | MI0010356_1 | 9.65 | up | 0.00E + 00 | 0.00E + 00 |
| miR-135b | MI0010334_1 | 9.25 | up | 0.00E + 00 | 0.00E + 00 |
| miR-181b | MI0008153_1 | 8.75 | up | 0.00E + 00 | 0.00E + 00 |
| miR-181b | MI0008127_1 | 8.75 | up | 0.00E + 00 | 0.00E + 00 |
| miR-196a | MI0010360_1 | 8.69 | up | 0.00E + 00 | 0.00E + 00 |
| miR-200b | MI0010361_1 | 8.11 | up | 0.00E + 00 | 0.00E + 00 |
| miR-181a | MI0008152_1 | 7.78 | up | 0.00E + 00 | 0.00E + 00 |
| miR-181a | MI0008126_1 | 7.62 | up | 0.00E + 00 | 0.00E + 00 |
| miR-15b | MI0008083_1 | 7.26 | up | 0.00E + 00 | 0.00E + 00 |
| miR-371 | MI0007996_1 | 7.11 | up | 0.00E + 00 | 0.00E + 00 |
| miR-371 | MI0007996_2_1 | 7.11 | up | 0.00E + 00 | 0.00E + 00 |
| miR-363 | MI0008176_1 | 7.01 | up | 0.00E + 00 | 0.00E + 00 |
| miR-103 | MI0010357_1 | 6.82 | up | 0.00E + 00 | 0.00E + 00 |
| miR-1841 | MI0008096_1 | 6.28 | up | 4.44E-16 | 6.49E-16 |
| miR-30b | MI0008013_1 | 5.82 | up | 0.00E + 00 | 0.00E + 00 |
| miR-200a | MI0010362_1 | 5.46 | up | 0.00E + 00 | 0.00E + 00 |
| miR-34c | MI0008106_1 | 5.43 | up | 0.00E + 00 | 0.00E + 00 |
| miR-146b | MI0008073_1 | 5.35 | up | 0.00E + 00 | 0.00E + 00 |
| miR-331 | MI0010394_1 | 5.24 | up | 0.00E + 00 | 0.00E + 00 |
| miR-147 | MI0010371_1 | 5.24 | up | 0.00E + 00 | 0.00E + 00 |
| miR-155 | MI0008078_1 | 5.10 | up | 0.00E + 00 | 0.00E + 00 |
| miR-20a | MI0008052_1 | 4.99 | up | 0.00E + 00 | 0.00E + 00 |
| miR-19b | MI0008054_1 | 4.96 | up | 0.00E + 00 | 0.00E + 00 |
| miR-19b | MI0008174_1 | 4.96 | up | 0.00E + 00 | 0.00E + 00 |
| miR-107 | MI0008072_1 | 4.92 | up | 0.00E + 00 | 0.00E + 00 |
| miR-181d | MI0008035_1 | 4.66 | up | 0.00E + 00 | 0.00E + 00 |
| miR-200c | MI0008070_1 | 4.53 | up | 0.00E + 00 | 0.00E + 00 |
| miR-345 | MI0008129_1 | 4.41 | up | 5.33E-15 | 7.54E-15 |
| miR-130a | MI0008029_1 | 4.08 | up | 0.00E + 00 | 0.00E + 00 |
| miR-29c | MI0008122_1 | 4.06 | up | 0.00E + 00 | 0.00E + 00 |
| miR-29c | MI0015960_1 | 4.06 | up | 0.00E + 00 | 0.00E + 00 |
| miR-15a | MI0008048_1 | 4.03 | up | 0.00E + 00 | 0.00E + 00 |
| miR-19a | MI0008051_1 | 3.84 | up | 0.00E + 00 | 0.00E + 00 |
| miR-16 | MI0008084_1 | 3.71 | up | 0.00E + 00 | 0.00E + 00 |
| miR-93 | MI0008110_1 | 3.56 | up | 0.00E + 00 | 0.00E + 00 |
| miR-1343 | MI0027953_1 | 3.53 | up | 0.00E + 00 | 0.00E + 00 |
| miR-7 | MI0010330_1 | 3.51 | up | 0.00E + 00 | 0.00E + 00 |
| miR-874 | MI0010429_1 | 3.51 | up | 4.76E-07 | 5.65E-07 |
| miR-103 | MI0008098_1 | 3.48 | up | 0.00E + 00 | 0.00E + 00 |
| miR-7 | MI0008033_1 | 3.46 | up | 0.00E + 00 | 0.00E + 00 |
| miR-27a | MI0008040_1 | 3.46 | up | 0.00E + 00 | 0.00E + 00 |
| miR-1839 | MI0008087_1 | 3.43 | up | 0.00E + 00 | 0.00E + 00 |
| miR-196a | MI0008068_1 | 3.43 | up | 0.00E + 00 | 0.00E + 00 |
| miR-20b | MI0010322_1 | 3.41 | up | 0.00E + 00 | 0.00E + 00 |
| miR-660 | MI0008186_1 | 3.39 | up | 0.00E + 00 | 0.00E + 00 |
| miR-215 | MI0010343_1 | 3.29 | up | 8.72E-06 | 9.96E-06 |
| miR-186 | MI0008108_1 | 3.27 | up | 0.00E + 00 | 0.00E + 00 |
| miR-495 | MI0008140_1 | 3.25 | up | 8.10E-12 | 1.07E-11 |
| miR-339 | MI0008115_1 | 3.25 | up | 0.00E + 00 | 0.00E + 00 |
| miR-421 | MI0008181_1 | 3.16 | up | 4.40E-14 | 6.13E-14 |
| miR-16 | MI0008049_1 | 3.14 | up | 0.00E + 00 | 0.00E + 00 |
| miR-27b | MI0008009_1 | 3.12 | up | 0.00E + 00 | 0.00E + 00 |
| miR-543 | MI0008139_1 | 3.10 | up | 0.00E + 00 | 0.00E + 00 |
| miR-205 | MI0010340_1 | 3.05 | up | 0.00E + 00 | 0.00E + 00 |
| miR-29a | MI0008022_1 | 3.03 | up | 0.00E + 00 | 0.00E + 00 |
| miR-192 | MI0008031_1 | 3.03 | up | 0.00E + 00 | 0.00E + 00 |
| miR-340 | MI0010391_1 | 3.01 | up | 0.00E + 00 | 0.00E + 00 |
| miR-503 | MI0008170_1 | 2.95 | up | 0.00E + 00 | 0.00E + 00 |
| miR-1296 | MI0028014_1 | 2.93 | up | 2.45E-10 | 3.11E-10 |
| miR-499 | MI0008059_1 | 2.91 | up | 0.00E + 00 | 0.00E + 00 |
| miR-7 | MI0008085_1 | 2.89 | up | 0.00E + 00 | 0.00E + 00 |
| miR-486 | MI0008027_2 | 2.87 | up | 4.44E-16 | 6.49E-16 |
| miR-212 | MI0008155_1 | 2.87 | up | 6.12E-08 | 7.41E-08 |
| miR-30d | MI0008012_1 | 2.81 | up | 0.00E + 00 | 0.00E + 00 |
| miR-615 | MI0010419_1 | 2.73 | up | 5.27E-05 | 5.99E-05 |
| miR-184 | MI0010337_1 | 2.71 | up | 4.44E-16 | 6.49E-16 |
| miR-130b | MI0008064_1 | 2.66 | up | 3.81E-10 | 4.77E-10 |
| miR-590 | MI0008114_1 | 2.64 | up | 0.00E + 00 | 0.00E + 00 |
| miR-23a | MI0008039_1 | 2.58 | up | 0.00E + 00 | 0.00E + 00 |
| miR-185 | MI0008065_1 | 2.55 | up | 0.00E + 00 | 0.00E + 00 |
| miR-335 | MI0008020_1 | 2.53 | up | 0.00E + 00 | 0.00E + 00 |
| miR-22 | MI0008157_1 | 2.51 | up | 0.00E + 00 | 0.00E + 00 |
| miR-125b | MI0008077_1 | 2.50 | up | 0.00E + 00 | 0.00E + 00 |
| miR-1307 | MI0008071_1 | 2.46 | up | 0.00E + 00 | 0.00E + 00 |
| miR-1301 | MI0027930_1 | 2.43 | up | 2.22E-16 | 3.32E-16 |
| miR-375 | MI0010368_1 | 2.38 | up | 4.60E-11 | 5.97E-11 |
| miR-23b | MI0008008_1 | 2.31 | up | 0.00E + 00 | 0.00E + 00 |
| miR-125b | MI0008103_1 | 2.30 | up | 0.00E + 00 | 0.00E + 00 |
| miR-324 | MI0010395_1 | 2.27 | up | 6.64E-09 | 8.25E-09 |
| miR-126 | MI0008154_1 | 2.25 | up | 1.22E-13 | 1.68E-13 |
| miR-542 | MI0008171_1 | 2.25 | up | 5.30E-11 | 6.77E-11 |
| miR-6529 | MI0027868_1 | 2.23 | up | 4.73E-11 | 6.08E-11 |
| miR-323 | MI0008137_1 | 2.19 | up | 8.21E-07 | 9.69E-07 |
| miR-365 | MI0001657_1 | 2.17 | up | 0.00E + 00 | 0.00E + 00 |
| miR-365 | MI0001647_1 | 2.16 | up | 0.00E + 00 | 0.00E + 00 |
| miR-92a | MI0008055_1 | 2.16 | up | 0.00E + 00 | 0.00E + 00 |
| miR-374b | MI0008180_1 | 2.16 | up | 0.00E + 00 | 0.00E + 00 |
| miR-1306 | MI0008066_1 | 2.13 | up | 0.00E + 00 | 0.00E + 00 |
| miR-29b | MI0008121_1 | 2.11 | up | 0.00E + 00 | 0.00E + 00 |
| miR-502 | MI0008187_1 | 2.10 | up | 0.00E + 00 | 0.00E + 00 |
| miR-92a | MI0008175_1 | 2.10 | up | 0.00E + 00 | 0.00E + 00 |
| miR-410 | MI0008149_1 | 1.97 | up | 3.84E-11 | 5.02E-11 |
| miR-101 | MI0008107_1 | 1.95 | up | 0.00E + 00 | 0.00E + 00 |
| miR-32 | MI0007992_1 | 1.95 | up | 4.17E-14 | 5.86E-14 |
| miR-376a | MI0008141_1 | 1.93 | up | 5.33E-15 | 7.54E-15 |
| miR-376a | MI0008142_1 | 1.93 | up | 5.33E-15 | 7.54E-15 |
| miR-376a | MI0008143_1 | 1.93 | up | 5.33E-15 | 7.54E-15 |
| miR-381 | MI0010390_1 | 1.92 | up | 0.00E + 00 | 0.00E + 00 |
| miR-454 | MI0010426_1 | 1.91 | up | 3.81E-10 | 4.77E-10 |
| miR-8859a | MI0027950_1 | 1.89 | up | 0.00E + 00 | 0.00E + 00 |
| miR-140 | MI0008100_1 | 1.88 | up | 0.00E + 00 | 0.00E + 00 |
| miR-425 | MI0008038_1 | 1.87 | up | 0.00E + 00 | 0.00E + 00 |
| miR-500 | MI0008185_1 | 1.85 | up | 0.00E + 00 | 0.00E + 00 |
| miR-2387 | MI0027966_1 | 1.84 | up | 1.14E-03 | 1.26E-03 |
| miR-30a | MI0008000_1 | 1.83 | up | 0.00E + 00 | 0.00E + 00 |
| miR-758 | MI0010424_1 | 1.82 | up | 3.43E-11 | 4.51E-11 |
| miR-329b | MI0010398_1 | 1.82 | up | 6.91E-09 | 8.54E-09 |
| miR-382 | MI0008145_1 | 1.80 | up | 2.95E-06 | 3.44E-06 |
| miR-24 | MI0008010_1 | 1.78 | up | 0.00E + 00 | 0.00E + 00 |
| miR-144 | MI0008158_1 | 1.75 | up | 9.22E-04 | 1.03E-03 |
| miR-24 | MI0008041_1 | 1.75 | up | 0.00E + 00 | 0.00E + 00 |
| miR-101 | MI0007995_1 | 1.73 | up | 0.00E + 00 | 0.00E + 00 |
| miR-301b | MI0010349_1 | 1.68 | up | 4.74E-06 | 5.49E-06 |
| miR-148b | MI0008069_1 | 1.68 | up | 0.00E + 00 | 0.00E + 00 |
| miR-485 | MI0008146_1 | 1.65 | up | 2.96E-08 | 3.60E-08 |
| miR-125a | MI0008005_1 | 1.65 | up | 0.00E + 00 | 0.00E + 00 |
| miR-379 | MI0008134_1 | 1.62 | up | 0.00E + 00 | 0.00E + 00 |
| let-7 g | MI0008036_1 | 1.62 | up | 0.00E + 00 | 0.00E + 00 |
| miR-18b | MI0010323_1 | 1.62 | up | 2.79E-06 | 3.27E-06 |
| miR-21 | MI0008165_1 | 1.61 | up | 0.00E + 00 | 0.00E + 00 |
| miR-505 | MI0010407_1 | 1.59 | up | 3.46E-13 | 4.71E-13 |
| miR-494 | MI0010404_1 | 1.57 | up | 0.00E + 00 | 0.00E + 00 |
| miR-380 | MI0008136_1 | 1.55 | up | 6.32E-06 | 7.27E-06 |
| miR-138a | MI0008056_1 | 1.52 | up | 9.49E-04 | 1.06E-03 |
| miR-26a | MI0008058_1 | −1.51 | down | 0.00E + 00 | 0.00E + 00 |
| miR-26a | MI0007990_1 | −1.51 | down | 0.00E + 00 | 0.00E + 00 |
| miR-222 | MI0010346_1 | −1.56 | down | 0.00E + 00 | 0.00E + 00 |
| miR-8884 | MI0027983_1 | −1.65 | down | 1.15E-08 | 1.41E-08 |
| miR-490 | MI0010372_1 | −1.66 | down | 1.82E-03 | 1.99E-03 |
| miR-30c | MI0008024_1 | −1.77 | down | 0.00E + 00 | 0.00E + 00 |
| miR-30c | MI0008001_1 | −1.77 | down | 0.00E + 00 | 0.00E + 00 |
| miR-99a | MI0008102_1 | −1.79 | down | 0.00E + 00 | 0.00E + 00 |
| miR-99a | MI0008075_1 | −1.79 | down | 0.00E + 00 | 0.00E + 00 |
| miR-127 | MI0008132_1 | −1.80 | down | 8.70E-05 | 9.83E-05 |
| miR-30e | MI0008023_1 | −1.87 | down | 5.28E-12 | 7.04E-12 |
| miR-889 | MI0027984_1 | −1.87 | down | 0.00E + 00 | 0.00E + 00 |
| miR-374a | MI0008179_1 | −2.33 | down | 0.00E + 00 | 0.00E + 00 |
| miR-455 | MI0007999_1 | −2.71 | down | 6.24E-14 | 8.63E-14 |
| miR-145 | MI0010359_1 | −2.81 | down | 0.00E + 00 | 0.00E + 00 |
| miR-574 | MI0008080_1 | −3.18 | down | 8.45E-08 | 1.01E-07 |
| miR-152 | MI0008162_1 | −3.25 | down | 0.00E + 00 | 0.00E + 00 |
| miR-148a | MI0008018_1 | −3.36 | down | 0.00E + 00 | 0.00E + 00 |
| miR-8865 | MI0027958_1 | −3.53 | down | 1.82E-03 | 1.99E-03 |
| miR-676 | MI0008188_1 | −3.71 | down | 3.65E-03 | 3.97E-03 |
| miR-105a | MI0010377_1 | −4.63 | down | 6.60E-08 | 7.94E-08 |
| miR-143 | MI0008092_1 | −5.78 | down | 0.00E + 00 | 0.00E + 00 |
| miR-196b | MI0008016_1 | −6.92 | down | 1.64E-02 | 1.77E-02 |
| miR-1 | MI0008118_1 | −7.52 | down | 0.00E + 00 | 0.00E + 00 |
| miR-1 | MI0008060_1 | −7.52 | down | 0.00E + 00 | 0.00E + 00 |
| miR-214 | MI0010342_1 | −9.13 | down | 4.89E-13 | 6.61E-13 |
| miR-504 | MI0010406_1 | −10.06 | down | 1.11E-16 | 1.67E-16 |
| miR-383 | MI0008026_1 | −10.41 | down | 1.28E-12 | 1.72E-12 |
| miR-199 | MI0008151_1 | −14.03 | down | 0.00E + 00 | 0.00E + 00 |
| miR-199 | MI0008042_1 | −14.03 | down | 0.00E + 00 | 0.00E + 00 |
| miR-199 | MI0008124_1 | −19.70 | down | 0.00E + 00 | 0.00E + 00 |
| miR-10a | MI0008161_1 | −41.07 | down | 0.00E + 00 | 0.00E + 00 |
| miR-206 | MI0008002_1 | −91.77 | down | 0.00E + 00 | 0.00E + 00 |