Table 3.
Lower abundant sperm proteins in normozoospermic samples that achieved pregnancy undergoing R-ICSI after IVF failure (n = 20)
| Swiss-Prot accession number | Protein name | Ratio (Mean ± SD) R-ICSI pregnancy/IVF pregnancy |
|---|---|---|
| P62937 | Peptidyl-prolyl cis–trans isomerase A | 0.76 ± 0.01 |
| Q5VTE0 | Putative elongation factor 1-alpha-like 3 | 0.76 ± 0.07 |
| Q9BXU7 | Ubiquitin carboxyl-terminal hydrolase 26 | 0.76 ± 0.08 |
| Q9BS86 | Zona pellucida-binding protein 1 | 0.75 ± 0.02 |
| P02743 | Serum amyloid P-component | 0.75 ± 0.02 |
| Q9UKU0 | Long-chain-fatty-acid–CoA ligase 6 | 0.75 ± 0.16 |
| Q8N4L4 | Spermatid maturation protein 1 | 0.74 ± 0.03 |
| Q8NEB7 | Acrosin-binding protein | 0.74 ± 0.09 |
| Q13748 | Tubulin alpha-3C/D chain | 0.74 ± 0.04 |
| P30101 | Protein disulfide-isomerase A3 | 0.74 ± 0.05 |
| P69905 | Hemoglobin subunit alpha | 0.72 ± 0.03 |
| Q1ZYL8 | Izumo sperm-egg fusion protein 4 | 0.71 ± 0.01 |
| Q6NXR0 | Interferon-inducible GTPase 5 | 0.70 ± 0.02 |
| P07477 | Trypsin-1 | 0.70 ± 0.10 |
| P84085 | ADP-ribosylation factor 5 | 0.68 ± 0.13 |
| Q13642 | Four and a half LIM domains protein 1 | 0.67 ± 0.05 |
| Q499Z3 | Schlafen-like protein 1 | 0.61 ± 0.06 |
| P00352 | Retinal dehydrogenase 1 | 0.61 ± 0.11 |
| Q06830 | Peroxiredoxin-1 | 0.60 ± 0.12 |
| Q96C74 | Ropporin-1-like protein | 0.55 ± 0.07 |
Annotations of altered proteins identified in sperm samples from the R-ICSI pregnancy group compared with the IVF pregnancy group. Values < 0.762 (P < 0.05) correspond to lower abundance in the R-ICSI pregnancy group. Standard deviation (SD)