FIGURE 4.
Effect of ACh and SNP on umbilical arteries. Ach induced contraction of UmbAs from both WT (A) and eNOS−/−(B) mice. Contraction was increased following PJ supplementation in both genotypes. SNP induced relaxation of UmbAs in WT (C) and eNOS−/−(D) mice and relaxation was potentiated by PJ supplementation in both genotypes. N = 11–13 dams, n = 28–36 vessels. ϕP < 0.05, ϕϕP < 0.01, ϕϕϕP < 0.001 significant effect of treatment two-way ANOVA.