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. 2018 Aug 14;9:1145. doi: 10.3389/fphys.2018.01145

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Copyright © 2018 Finn-Sell, Cottrell, Greenwood, Dilworth, Cowley, Sibley and Wareing.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Litter size, fetal and placental weight. Litter size (A) was significantly reduced by PJ treatment, in both eNOS^−/− and WT mice (^ϕP < 0.05, two-way ANOVA). Fetal weight was lower in eNOS^−/− mice irrespective of treatment (B), ^∗∗∗p < 0.001, two-way ANOVA. There was no effect of genotype or treatment on placental weight (C). N = 14–20 l. Fetal weight distribution curves (D) showed no differences in weight distribution following treatment, n = 78–143 pups from N = 14–20 l.