Figure 10.

PMN and macrophage phagocytosis detection. A, B) After 15-LOX siRNA treatment, peritoneal-derived PMNs (A) and macrophages (B) from BALB/c and B6 mice were exposed to an enzyme-labeled phagocytosis pathogen (E. coli for PMNs; zymosan for macrophages). Scrambled siRNA was used as a negative control. C) Efficiency of knockdown as measured by ELISA for 12/15-LOX as represented in PMNs. Data are reported as means ± sd. *P < 0.05 vs. BALB/c control, ^#P < 0.05 vs. B6 control (unless otherwise noted).