Figure 5. Adult social interaction.
Behaviors measured included a) active investigation time, b) number of active bouts, c) passive interaction time, and d) number of social avoidance behaviors. Female rats actively investigated more times than male rats regardless of treatment (a and b). Vehicle female rats passively interacted more than vehicle treated males and clodronate treated females (c). Clodronate treated rats showed more social avoidance behaviors than vehicle treated rats (d). Data are presented are ±SEM, *p < 0.05, ****p < 0.0001, and #p < 0.05 between sex or between treatment. n = 9 for clodronate treated males, n = 10 for vehicle treated males, n = 11 for clodronate treated and vehicle treated females.