Table 2.
Side effects of conditioning regimen
| BEAM n = 174 | BeEAM n = 63 | p-value | |
|---|---|---|---|
| Nausea, n (%): grade 2–4 grade 3–4 |
56 (32.1) 24 (13.8) |
26 (41.3) 7 (11.1) |
0.19 0.59 |
| Vomiting, n (%): grade 2–4 grade 3–4 |
22 (12.6) 8 (4.6) |
9 (14.3) 2 (3.2) |
0.74 0.63 |
| Mucositis, n (%): grade 2–4 grade 3–4 |
29 (16.7) 11 (6.3) |
11 (17.5) 5 (7.9) |
0.88 0.66 |
| Diarrhoea, n (%) grade 2–4 grade 3–4 |
26 (14.9) 8 (4.6) |
13 (20.6) 4 (6.35) |
0.3 0.59 |
| Pneumonia, n (%): grade 2–4 grade 3–4 |
6 (3.5) 3 (1.7) |
2 (3.2) 1 (1.6) |
0.92 0.94 |
| Febrile neutropaenia, n (%): grade 2–4 grade 3–4 |
36 (20.7) 36 (20.7) |
13 (20.6) 13 (20.6) |
0.99 0.99 |
| Hypokalaemia, n (%): grade 2–4 grade 3–4 |
0 (0) 0 (0) |
3 (4.8) 3 (4.8) |
0.004 0.004 |
| Arterial hypertension, n (%): grade 2–4 |
0 (0) |
2 (3.2) |
0.02 |
| Elevated liver enzymes, n (%): grade 2–4 grade 3–4 |
3 (1.7) 2 (1.2) |
1 (1.6) 1 (1.6) |
0.94 0.79 |
| Cardiac arrhythmias, n (%): grade 2–4 |
3 (1.7) |
0 (0) |
0.3 |
| Metrorrhagia, n (%): grade 2–4 |
8 (4.6) |
0 (0) |
0.08 |
| Allergic reaction, n (%): grade 2–4 grade 3–4 |
5 (2.9) 2 (1.2) |
0 (0) 0 (0) |
0.17 0.39 |
| Kidney injury, n (%): grade 2–4 |
1 (0.6) |
1 (1.6) |
0.45 |