Fig. 7.

Comparison of occupation frequency p as function of the unspecific dissociation rate constant µ₁ between a promoter activated by a single TF (TF, red line), a promoter activated by a dimer formed on DNA (Dimer on DNA, blue line) and by a dimer formed in the nucleoplasm (Dimer in nucleoplasm, dashed blue line), when an inhibitory competitor of the TF is present (Competitor ζ₁= 1 s⁻¹, yellow line) and when the competitor has a larger unspecific dissociation rate constant (Competitor ζ₁= 25 s⁻¹, dashed yellow line). Simulation parameters are: N = 100, C = 100, B = 10⁴, λ₁₀= Λ₁₀= 4·10⁻⁴ s⁻¹, λ₀= Λ₀= 10⁻⁵ s⁻¹, λ₂= Λ₂= 4 s⁻¹, μ = 10⁻¹ s⁻¹, ζ = 10⁻³ s⁻¹. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)