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. Author manuscript; available in PMC: 2018 Aug 21.
Published in final edited form as: Nat Genet. 2013 Sep 1;45(10):1190–1197. doi: 10.1038/ng.2743

Figure 5.

Figure 5

Effect of Rv3792 synonymous mutations on Rv3792 and embC mRNA levels. RNA was extracted from cultures grown to mid-log phase. Transcript levels were analyzed by qRT-PCR, and fold changes were determined by comparison to levels in the 210 strain after normalization to 16S rRNA levels. (a–e) Relative mRNA levels of 5′ Rv3792 (a), 3′ Rv3792 (b), embC (c), embB (d) and Rv3806c (e). Means and s.d. are derived from three independent experiments. Large increases in the expression of 3′ Rv3792 and of embC are seen only in the Rv3792 mutants. No strain has increased Rv3806c expression; embB expression is mildly decreased in strain 4C31-16C1-24C1.