Table 3.
Comparison of the examination groups with differentiation between acute and chronic infections according to laboratory evaluations including inflammatory, osteological and protein parameters
| Acute infection | Chronic infection | P-value | |
|---|---|---|---|
| Number of subjects (excluded antiosteoporotic-treated patients) | 25.4% (15/59) | 74.6% (44/59) | |
| Hemoglobin in mmol/L (7.2–10.0) | 5.3±1.53 | 6.5±1.34 | 0.015 |
| Leukocytes in exp9/L (3.5–9.8) | 11.4±4.3 | 7.6±1.4 | <0.001 |
| C-reactive protein in mg/L (<5) | 176.3±64 | 27.3±54 | <0.001 |
| Calcium in mmol/L (2.19–2.54) | 2.13±0.18 | 2.23±0.14 | 0.010 |
| Patients with lowered Ca values in % | 73.3% (11/15) | 38.6% (17/44) | <0.001 |
| Alkaline phosphatase in µg/L (5.7–32.9) | 1.59±0.53 | 1.59±0.65 | 0.880 |
| 25 OH vitamin D3 in ng/mL (20.0–47.9) | 8.3±5.98 | 21.6±8.40 | 0.002 |
| Patients with 25 OH vitamin D3 deficiency <20 ng/mL in % | 86.7% (13/15) | 45.5% (20/44) | <0.001 |
| Patients with 25 OH vitamin D3 insufficiency: 20–29 ng/mL in % | 13.3% (2/15) | 50% (22/44) | <0.001 |
| Patients with normal 25 OH vitamin D3 >30 ng/mL in % | 0 | 4.5% (2/44) | |
| Parathyroid hormone in pmol/L (1.6–6.9) | 3.99±1.3 | 3.80±2.6 | 0.541 |
| Albumin in g/L (35–52) | 28.0±7.1 | 37.7±5.5 | 0.030 |
| Patients with lowered albumin-values in % | 80.0% (12/15) | 36.4% (16/44) | <0.001 |
| Serum protein in g/L (63–83) | 59±7.12 | 69.3±6.32 | 0.040 |
| Patients with lowered serum protein values in % | 86.7% (13/15) | 22.7% (10/44) | <0.001 |
| Creatinine in µmol/L (45–84) | 75±36.1 | 77±21.9 | 0.390 |
| Alanine aminotransferase in µkat/L (0.17–0.58) | 0.33±0.13 | 0.32±0.13 | 0.700 |
| Time spending outdoors in hours | 1±0.83 | 1±0.94 | 0.340 |
Notes: Pathological values are highlighted in italics. The values are expressed as median (±mean deviation) or as percentage (share/total). The standard values or the physiological range are given in brackets.