Table 1.

Influence of the GABAergic system in amygdala responses to stress.

Types of stress		Regions	Changes in GABAergic system	References
Acute	Forced swimming	BLA	Activation of GPR30 increased the inhibitory synaptic transmission	Tian et al., 2013
		BLA	Promote GABAergic transmission	Feng et al., 2013
		BLA	Disrupted the cannabinoid receptor type 1-associated modulation of the GABAergic system	Bedse et al., 2015
	Restraint stress	CeA	Elevate baseline GABAergic responses	Ciccocioppo et al., 2014
	Maternal separation	CeA	Increase in the density V1a transcripts of GABAergic neurons	Hernández et al., 2016
		BLA	Decrease c-Fos expression in a subset of GABAergic interneurons	Lukkes et al., 2012
	Glucocorticoid administration	BLA	Suppress spontaneous GABAergic synaptic currents	Di et al., 2016
	DEX administration		Upregulate GABA release and GABAergic neuronal spiking	Wang et al., 2016
	Ethanol consumption	BLA	Increase GABAergic transmission	Varodayan et al., 2017
Chronic	Water-deprivation	CeA	Increase in the density V1a transcripts of GABAergic neurons	Hernández et al., 2016
	Chronic unpredictable	CeA	Regulation of GABAA receptors	Alò et al., 2015
		CeA and BNST	Promote GABAergic transmission	Partridge et al., 2016
		CeA	Down-regulation of GAD65 expression	Ortiz et al., 2015
	Corticosterone administration	LA and CeA	Decreased GABAA α-2 subunit density	Skórzewska et al., 2015
	DEX administration		Increase cleaved caspase-3 and GABAergic calcium-binding protein	Zuloaga et al., 2011
			Enhanced the responsiveness of GABA receptors	Wang et al., 2016
	Ethanol consumption	BLA	Disrupted the cannabinoid receptor type 1-associated modulation of the GABAergic system	Varodayan et al., 2017
	Prenatal stress		Influenced the chloride transporters K-Cl cotransporter 2, Na-K-Cl cotransporter 1	Ehrlich et al., 2015
	Peripuberty stress	LA, BLA, and CeA	Decrease in the expression of GAD and GABAA receptor subunits	Tzanoulinou et al., 2014
			Regulation of the GABAA receptor subunits	Jacobson-Pick and Richter-Levin, 2012

BLA, basolateral nucleus; CeA, central amygdala; BNST, bed nucleus of the stria terminalis; LA, lateral amygdala; GPR30, oxG-protein-coupled receptor 30;GABA, oxγ-aminobutyric acid; BLA, basolateral nucleus; GAD, glutamic acid decarboxylase.