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. Author manuscript; available in PMC: 2018 Aug 21.
Published in final edited form as: Endocrinology. 2007 Dec 13;149(3):1129–1135. doi: 10.1210/en.2007-1241

Figure 4.

Figure 4

NE acts through α1 and β adrenergic receptors to suppress GnRH neuron excitability. A. Perforated-patch recording from a GnRH neuron of a 33 day old male mouse showing hyperpolarizing responses to NE (100µM) and phenylephrine (PE; 30µM) followed by a partial suppression of the NE hyperpolarization by prazosin (Praz; 10µM) and then recovery of the NE action. B. Perforated-patch recording from a GnRH neuron of a 60 day old male mouse showing lack of effect of guanabenz (GBZ; 10µM). C. Perforated-patch recording from a GnRH neuron of a 42 day old female mouse showing hyperpolarizing responses to Iso (100µM), PE (30µM) and NE (100µM).

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