Table S1.
Summary of the experiments performed
| Experiment | Content of Tween-80 (w/v) (%) | MX:BSA | Content of MX (mg mL−1) | Particle size (nm) | Particle size after 24 h (nm) | Stability time (at 4°C) |
|---|---|---|---|---|---|---|
| 1 | 0.1 | 1:5 | 5 | 255.5 | 592.3 | ND |
| 2 | 0.2 | 1:5 | 5 | 179.4 | 445.6 | ND |
| 3 | 0.3 | 1:5 | 5 | 78.42 | 78.61 | >15 days |
| 4 | 0.4 | 1:5 | 5 | 71.5 | 187.9 | ND |
| 5 | 0.3 | 1:1 | 5 | 90.12 | Precipitation appeared | <1 day |
| 6 | 0.3 | 1:3 | 5 | 87.82 | 114.37 | 3 days |
| 7 | 0.3 | 1:10 | 5 | 108.17 | 139.25 | 3 days |
| 8 | 0.3 | 1:7 | 5 | 85.81 | 90.49 | 7 days |
| 9 | 0.3 | 1:5 | 2.5 | 92.35 | ND | >15 days |
| 10 | 0.3 | 1:5 | 7.5 | 59.21 | ND | <3 days |
Note: Stability time: the time that precipitation did not appear.
Abbreviations: BSA, bovine serum albumin; MX, meloxicam; ND, not determined.