Table 2.
Meta-Analysis of Studies Regarding the Relationship between Selenium and Prostate Cancer Based on Country, Type of study and sample of selenium. random effects model
Variable | Study(Na) | Case | Control | I2(%) | 95% CIb | RRc | |
---|---|---|---|---|---|---|---|
Country | USA | 23 | 31,691 | 70,385 | 51.6 | 0.78,1.02 | 0.89 |
Austria | 1 | 70 | 80 | 0.21,2.60 | 0.74 | ||
United Kingdim | 1 | 300 | 300 | 0.73,2.10 | 1.24 | ||
Hawaii | 1 | 450 | 936 | 0.59,1.14 | 0.82 | ||
Europe | 1 | 959 | 1,059 | 0.22,4.15 | 0.96 | ||
China | 1 | 133 | 265 | 0.98,1.02 | 1 | ||
Iran | 1 | 62 | 68 | 0.06,0.45 | 0.16 | ||
Finland | 1 | 317 | 28,816 | 0.43,1.66 | 0.84 | ||
Sweden | 1 | 164 | 121 | 0.11,0.79 | 0.3 | ||
Denmark | 1 | 784 | 784 | 0.94,1.08 | 1.01 | ||
Netherlands | 2 | 540 | 1,211 | 84.4 | 0.27,0.92 | 0.5 | |
Type of study | Case-control | 19 | 8,639 | 16,967 | 59.1 | 0.80,1.00 | 0.89 |
Cohort | 6 | 3,786 | 66,682 | 85.5 | 0.52,1.14 | 0.77 | |
Randomized controlled trial | 9 | 23,994 | 21,644 | 54.3 | 0.74,1.09 | 0.9 | |
Sample of selenium | Serum | 6 | 1,983 | 2,913 | 62.5 | 0.51,0.95 | 0.69 |
Plasma | 6 | 2,982 | 2,637 | 70.1 | 0.61,1.17 | 0.85 | |
Nail | 6 | 2,189 | 3263 | 74.8 | 0.41,1.05 | 0.66 | |
Diet | 7 | 5,206 | 74,814 | 0 | 0.98,1.02 | 1 | |
Selenium supplement and placebo | 9 | 23,994 | 21,644 | 54.3 | 0.74,1.09 | 0.9 |
, Number ;
, Confidence interval ;
, Relative risk