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. 2018;19(6):1431–1437. doi: 10.22034/APJCP.2018.19.6.1431

Table 2.

Meta-Analysis of Studies Regarding the Relationship between Selenium and Prostate Cancer Based on Country, Type of study and sample of selenium. random effects model

Variable Study(Na) Case Control I2(%) 95% CIb RRc
Country USA 23 31,691 70,385 51.6 0.78,1.02 0.89
Austria 1 70 80 0.21,2.60 0.74
United Kingdim 1 300 300 0.73,2.10 1.24
Hawaii 1 450 936 0.59,1.14 0.82
Europe 1 959 1,059 0.22,4.15 0.96
China 1 133 265 0.98,1.02 1
Iran 1 62 68 0.06,0.45 0.16
Finland 1 317 28,816 0.43,1.66 0.84
Sweden 1 164 121 0.11,0.79 0.3
Denmark 1 784 784 0.94,1.08 1.01
Netherlands 2 540 1,211 84.4 0.27,0.92 0.5
Type of study Case-control 19 8,639 16,967 59.1 0.80,1.00 0.89
Cohort 6 3,786 66,682 85.5 0.52,1.14 0.77
Randomized controlled trial 9 23,994 21,644 54.3 0.74,1.09 0.9
Sample of selenium Serum 6 1,983 2,913 62.5 0.51,0.95 0.69
Plasma 6 2,982 2,637 70.1 0.61,1.17 0.85
Nail 6 2,189 3263 74.8 0.41,1.05 0.66
Diet 7 5,206 74,814 0 0.98,1.02 1
Selenium supplement and placebo 9 23,994 21,644 54.3 0.74,1.09 0.9
a

, Number ;

b

, Confidence interval ;

c

, Relative risk