Figure 1.
Schematic illustration representing the outline of synthesis and pulmonary codelivery of DOX and MRP1 siRNA.
Abbreviations: DOX, doxorubicin hydrochloride; MDR, multidrug resistance; MRP, MDR-associated proteins; PLLA, poly-l-lactide; siRNA, short-interfering RNA; siRNA-CS, siRNA-loaded chitosan; SAS, supercritical antisolvent.