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. 2018 Jun 23;17(8):974–984. doi: 10.1080/15384101.2018.1464834

Figure 4.

Figure 4.

LINC00152 inhibits cell cycle progression by controlling CCND1 in HCC cells. (a) Fluorescence-activated cell sorting (FACS) analysis showed a marked increase in the proportion of cells in G0/G1 in the LINC00152-knockdown Huh7 and HCCLM3 cells (* p < 0.05, ** p < 0.01, *** p < 0.001). (b) The CCND1 mRNA and protein expression levels were reduced in qPCR and western blot analyses following LINC00152 knockdown (** p < 0.01, *** p < 0.001). (c) LINC00152 mRNA expression was positively correlated with CCND1 mRNA expression in 32 HCC specimens as detected by qRT–PCR (R2 = 0.354, p < 0.001).