S. mutans UA159 gene expression profile for ΔtsaC, ΔtsaB, ΔtsaD, ΔtsaE, and prrC genes during growth in Biofilm and Rich media (BHI). A. Fold change difference of each of the genes with respect to 4h time point (calibrator). * indicates statistical significance (P < 0.05, Student-Newman-Keuls Test) relative to calibrator sample. B. Fold change difference in gene expression at each time point in Biofilm media with respect to Rich media (calibrator). * indicates statistical significance (P < 0.05, Two-tailed T-Test) relative to calibrator sample.