Key resources table.
| Reagent type (species) or resource |
Designation | Source or reference | Identifiers | Additional information |
|---|---|---|---|---|
| Biological sample (human) |
Patient brains samples | NA | All identifiers are provided in Supplementary file 1A |
|
| Antibody | hnRNP H (rabbit) | Bethyl, A300-511 | ||
| Antibody | hnRNP H (rabbit, Co-IP) | ThermoFisher, PA5-27610 | ||
| Antibody | TDP-43 (rabbit) | Proteintech, 10782–2-AP | ||
| Antibody | TDP-43 human specific (mouse) |
Proteintech, 60019–2-Ig | ||
| Antibody | hnRNP A1 (mouse) | Sigma, 4B10 | ||
| Antibody | FUS (mouse) | Santa Cruz Biotechnologies, H-6 | ||
| Antibody | GAPDH (rabbit) | Sigma, G9545 | ||
| Antibody | U2AF65 (mouse) | Sigma, U4758 | ||
| Antibody | SMN (mouse) | Sigma, S2944 | ||
| Antibody | Histone H3 (rabbit) | Abcam, 1791 | ||
| Antibody | FLAG-M2 (mouse) | Sigma, F1804 | ||
| Antibody | Actin (rabbit) | Sigma, A2066 | ||
| Antibody | C9ORF72 (rabbit) | Novus, 1086CGP | ||
| Software, algorithm | Leafcutter | Li et al. (2018) |