Table 1. Statin's effects on various adipocytes affecting molecules.

Molecule	Physiological effects	Statin's effects
Adiponectin	↓ Hepatic glucose production ↑ Insulin secretion 26 29	Decreased by atorvastatin, simvastatin Neutral or increase by atorvastatin, pravastatin, simvastatin, fluvastatin 24 25
Visfatin	Mimics the effects of insulin binding the insulin receptor providing hypoglycemic effects 30	Downregulation by rosuvastatin, atorvastatin Neutral effect by simvastatin 24 31
Resistin	↑ Blood glucose ↑ Glycogenolysis ↑ Gluconeogenesis	Little or no effect by statins (mostly atorvastatin studies) 24 29
Leptin	Effects on insulin signaling and hepatic glucose production 29 Performs a similar function as compared with insulin 32	Suppression by rosuvastatin, simvastatin, and atorvastatin Neutral effect by pravastatin, atorvastatin, simvastatin 24 25