Effect of Kavain treatment on PGC-1α and inflammatory markers on primary adipocytes isolated from adipose tissue of mice after intraperitoneal injection of P.gingivalis. RT-PCR investigation showed mRNA expression of (A) PGC-1α, (B) TNF-α, (C) IL-6, (D) NF-kB, (E) NOV, in WT-control, P.gingivalis and P.gingivalis + Kavain exposed mice. Results are mean±SE, n=3–4, *p<0.05 vs. WT, #p< 0.05 vs. P.gingivalis.