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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: J Immunol. 2018 Jul 16;201(5):1442–1451. doi: 10.4049/jimmunol.1800014

Figure 6.

Figure 6

Dock2−/− mice have defects in recirculating B cells, marginal zone B cells, B1a cells. Comparison of B cell populations in WT (n = 12), Nod2−/−Dock2mut (labelled as Nod2−/− in previous figures) (n = 6), and Dock2−/− (n = 11) mice. (A) Number of of total live cells and B220+ CD19+ B cells in the spleen. (B) Representative plot and percentage of bone marrow recirculating B cells (B220high IgM+). (C) Representative plot and percentages of marginal zone (CD21 high CD23 low) and follicular (CD21 low CD23 high) B cells in the spleen. (D) Representative plot and percentages of B1a cells (B220 low, CD19+ CD5+) from peritoneal lavage and spleen. Data is representative of three independent experiments. ns p > 0.05, **p ≤ 0.01, ****p ≤ 0.0001 by two-tailed Mann-Whitney.