Table I.
Research subjects’ characteristics and laboratory results
| Characteristics | Steroid-naive Means (ranges) |
Steroid-dependent Means (ranges) |
|
|---|---|---|---|
| Subjects (n) | 10 | 8 | |
| Sex: males/females | 5/5 | 2/6 | |
| Age (y) | 36.8 (26 - 54) | 41.5 (30 - 55) | |
| P value (naive vs. dependent) | 0.32 | ||
| Body mass index (kg/m2) | 29.8 (21.9 - 39.6) | 27.8 (19.1 - 47.8) | |
| P value (naive vs. dependent) | 0.62 | ||
| Blood Eosinophils (cells/μl) | 150 (50 - 460) | 330 (150 - 650) | |
| P value (naive vs. dependent) | 0.03 | ||
| FeNO (ppb) | Fasted state | 17.7 (4.7 - 43.6) | 24.8 (8.9 - 81.8) |
| Refed state | 19.4 (5.6 - 42.5) | 24.9 (6.0 - 82.7) | |
| P value (refed vs. fasted) | 0.75 | 0.99 | |
| FEV1 (% predicted) | Fasted state | 76.9 (68 - 100) | 85.8 (76 - 109) |
| Refed state | 87.0 (67 - 100) | 90.1 (79 - 112) | |
| P value (refed vs. fasted) | 0.29 | 0.42 | |
| Glucose (mg/dl) | Fasted state | 79.6 (69 - 91) | 82.4 (76 - 89) |
| Refed state | 94.6 (73 - 121) | 87.3 (73 - 104) | |
| P value (refed vs. fasted) | 0.01 | 0.20 | |
| Insulin (mU/ml) | Fasted state | 7.0 (3.5 - 12.5) | 5.5 (1.4 - 17.6) |
| Refed state | 31.9 (6.8 - 78.4) | 22.1 (7.4 - 77.9) | |
| P value (refed vs. fasted) | 0.003 | 0.07 | |
| Growth Hormone (ng/ml) | Fasted state | 1.4 | 3.5 |
| Refed state | 1.0 | 1.1 | |
| P value (refed vs. fasted) | 0.55 | 0.17 | |
The p values were calculated using paired student t-test analysis. The level for significance was defined as p< 0.05 and significant p value are indicated in boldface. FeNO, Fractional exhaled nitric oxide; FEV1, Forced expiratory volume in 1 second.