Table 3.
Summary of univariate and multivariate Cox regression analysis of overall survival duration
| Parameter | Case number | p | HR | 95% CI |
|---|---|---|---|---|
| Univariate analysis | ||||
| Sex (Male vs. Female) | 53/37 | 0.149 | 0.67 | 0.39–1.15 |
| Age (≥63 vs. < 63) | 46/44 | 0.0673 | 0.61 | 0.36–1.04 |
| Tumor size (≥5.5 vs. < 5.5) | 42/48 | 0.1179 | 1.527 | 0.90–2.60 |
| Location (Upper vs. Middle vs. Low vs. Remnant) | 10/27/51/2 | 0.3653 | – | – |
| T classification (T1/T2 vs. T3/T4) | 14/76 | 0.0031 | 0.39 | 0.21–0.73 |
| N classification (No vs. N1/N2/N3) | 22/68 | < 0.0001 | 0.26 | 0.15–0.45 |
| YAP (Low vs. High) | 37/53 | < 0.0001 | 0.23 | 0.14–0.40 |
| YAP (Nuclear high vs. Nuclear low) | 25/65 | < 0.0001 | 0.17 | 0.09–0.35 |
| YAP (Cytoplasm high vs. Cytoplasm low) | 69/21 | 0.4020 | 0.77 | 0.41–1.43 |
| p-PTEN (Score: 0 vs. 1 vs. 2 vs. 3 vs. 4 vs. 5 vs. 6) | 10/5/31/36/6/0/2 | < 0.0001 | – | – |
| Multivariate analysis | ||||
| T classification (T1/T2 vs. T3/T4) | 14/76 | 0.043 | 2.92 | 1.03–8.28 |
| N classification (No vs. N1/N2/N3) | 22/68 | 0.004 | 4.66 | 1.61–13.46 |
| YAP (Low vs. High) | 37/53 | 0.001 | 3.70 | 1.70–8.04 |
| YAP (Nuclear high vs. Nuclear low) | 25/65 | 0.028 | 1.98 | 1.07–3.63 |
| p-PTEN (Score: 0 vs. 1 vs. 2 vs. 3 vs. 4 vs. 5 vs. 6) | 10/5/31/36/6/0/2 | 0.045 | 0.80 | 0.65–1.00 |