Table 1.
UBC patients’ characteristics and clinical-pathologic features for the whole cohort and different racial groups.
| Total (n = 377400) | NHW (n = 325612) | HW (n = 17613) | Black (n = 19646) | API (n = 14147) | P | |
|---|---|---|---|---|---|---|
| Gender | <0.001 | |||||
| Male | 282714 (74.9) | 245806 (75.5) | 12953 (73.5) | 13073 (66.5) | 10586 (74.8) | |
| Female | 94686 (25.1) | 79806 (24.5) | 4660 (26.5) | 6573 (33.5) | 3561 (25.2) | |
| Marital Status | <0.001 | |||||
| Single | 34171 (9.6) | 26861 (8.7) | 2237 (13.4) | 3759 (20.4) | 1258 (9.4) | |
| Married | 231638 (65.0) | 203205 (66.1) | 10354 (62.1) | 8452 (45.8) | 9409 (70.2) | |
| Separated/d/w | 90451 (25.4) | 77329 (25.2) | 4078 (24.5) | 6251 (33.9) | 2736 (20.4) | |
| Age group | ||||||
| 0–39 | 5124 (1.4) | 3970 (1.2) | 521 (3.0) | 364 (1.9) | 246 (1.7) | <0.001 |
| 40–64 | 103273 (27.4) | 87161 (26.8) | 5533 (31.4) | 6550 (33.3) | 3883 (27.5) | |
| 65–84 | 223595 (59.3) | 194596 (59.8) | 9714 (55.2) | 10850 (55.2) | 8248 (58.3) | |
| 85+ | 45398 (12.0) | 39881 (12.3) | 1844 (9.6) | 1880 (9.6) | 1767 (12.5) | |
| Age at diagnosis | 70.7 ± 14.9 | 70.9 ± 12.4 | 66.6±13.7 | 68.6 ± 12.9 | 70.7 ± 18.6 | <0.001 |
| Survival time (month) | 50.0 ± 93.0 | 51.0 ± 95.0 | 43.0 ± 85.0 | 33.0 ± 77.0 | 48.0 ± 94.0 | <0.001 |
| Histological types | <0.001 | |||||
| PTCC | 246724 (65.4) | 215800 (66.3) | 11130 (63.2) | 10786 (54.9) | 8721 (61.7) | |
| NPTCC | 102611 (27.2) | 87054 (26.7) | 4862 (27.6) | 6362 (32.4) | 4271 (30.2) | |
| CARCINOMA | 6364 (1.7) | 5303 (1.6) | 311 (1.8) | 476 (2.4) | 270 (1.9) | |
| SCC | 5194 (1.4) | 4091 (1.3) | 303 (1.7) | 630 (3.2) | 166 (1.2) | |
| Others | 16507 (4.4) | 13364 (4.1) | 1007 (5.7) | 1392 (7.1) | 719 (5.1) | |
| Grade | <0.001 | |||||
| Grade I | 53673 (16.9) | 47393 (17.3) | 2344 (16.1) | 2344 (14.7) | 1541 (13.1) | |
| Grade II | 107825 (34.0) | 94567 (34.5) | 4851 (33.3) | 4537 (28.4) | 3769 (31.9) | |
| Grade III | 84665 (26.7) | 72609 (26.5) | 3806 (26.1) | 4975 (31.2) | 3206 (27.1) | |
| Grade IV | 70885 (22.4) | 59857 (21.8) | 3575 (24.5) | 4101 (25.7) | 3295 (27.9) | |
| Stage | <0.001 | |||||
| stage II | 275889 (76.4) | 241037 (77.2) | 12403 (74.0) | 12073 (65.6) | 10075 (74.6) | |
| stage III | 70845 (19.6) | 59712 (19.1) | 3414 (20.4) | 4885 (26.6) | 2791 (20.7) | |
| stage IV | 14422 (4.0) | 11401 (3.7) | 936 (5.6) | 1430 (7.8) | 645 (4.8) | |
| Tumor size (mm) | 41.1 ± 49.2 | 40.9 ± 47.2 | 41.3 ± 61.1 | 46.3 ± 58.9 | 38.5 ± 58.2 | <0.001 |
| Regional nodes | <0.001 | |||||
| All nodes negative | 54839 (92.2) | 47552 (92.5) | 2518 (90.7) | 2763 (90.1) | 1978 (90.7) | |
| ≥1 nodes positive | 4642 (7.8) | 3873 (7.5) | 259 (9.3) | 305 (10.0) | 204 (9.4) | |
| Location | <0.001 | |||||
| NOS | 156540 (41.5) | 134286 (41.2) | 7325 (41.6) | 8882 (45.2) | 5861 (41.4) | |
| Lateral wall of bladder | 74042 (19.6) | 65004 (20.0) | 3266 (18.5) | 3061 (15.6) | 2640 (18.7) | |
| Overlapping lesion of bladder | 41538 (11.0) | 35805 (11.0) | 1936 (11.0) | 2361 (12.0) | 1409 (10.0) | |
| Posterior wall of bladder | 32095 (8.5) | 27599 (8.5) | 1632 (9.2) | 1515 (7.7) | 1328 (9.4) | |
| Trigone of bladder | 22677 (6.0) | 19673 (6.0) | 1059 (6.0) | 1100 (5.6) | 830 (5.9) | |
| Ureteric orifice | 17362 (4.6) | 15538 (4.8) | 685 (3.9) | 560 (2.8) | 555 (3.9) | |
| Dome of bladder | 13755 (3.6) | 11483 (3.5) | 720 (4.1) | 930 (4.7) | 611 (4.3) | |
| Bladder neck | 11734 (3.1) | 9878 (3.0) | 573 (3.3) | 729 (3.7) | 543 (3.8) | |
| Anterior wall of bladder | 7116 (1.9) | 5978 (1.8) | 366 (2.1) | 453 (2.3) | 313 (2.2) | |
| Urachus | 541 (0.1) | 368 (0.1) | 60 (0.3) | 55 (0.3) | 57 (0.4) | |
| Treatment | <0.001 | |||||
| Surgery | 285607 (76.9) | 248900 (77.6) | 13244 (76.1) | 13248 (69.0) | 10215 (73.2) | |
| SC | 41615 (11.2) | 35417 (11.0) | 1929 (11.0) | 2308 (12.0) | 1961 (14.1) | |
| No treatment | 20298 (5.5) | 16480 (5.1) | 1241 (7.1) | 1741 (9.7) | 836 (6.0) | |
| SR | 11555 (3.1) | 9822 (3.1) | 405 (2.3) | 883 (4.6) | 445 (3.2) | |
| SRC | 7905 (2.1) | 6651 (2.1) | 349 (2.0) | 589 (3.1) | 316 (2.3) | |
| Chemotherapy | 2017 (0.5) | 1619 (0.5) | 137 (0.8) | 186 (1.0) | 75 (0.5) | |
| Radiation | 1706 (0.5) | 1380 (0.4) | 65 (0.4) | 183 (1.0) | 78 (0.6) | |
| RC | 562 (0.2) | 428 (0.1) | 34 (0.2) | 66 (0.3) | 34 (0.2) |
Cancers diagnosed 1973–2014 in the SEER 9 database. For a survival time, median ± interquartile range, for age at diagnosis and tumor size, mean ± standard deviation and for a categorical variable, count (percentage).