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. 2018 Jul 15;9(4):685–700. doi: 10.1002/jcsm.12311

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© 2018 The Authors. Journal of Cachexia, Sarcopenia and Muscle published by John Wiley & Sons Ltd on behalf of the Society on Sarcopenia, Cachexia and Wasting Disorders

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

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Growth of the ES‐2 tumour affects bone quality. Representative three‐dimensional rendering of microcomputed tomography scan images and quantification of bone volume fraction (BV/TV), trabecular thickness (Tb.Th), trabecular separation (Tb.Sp), trabecular number (Tb.N), and trabecular connectivity density (Conn.Dn) in the femurs (A) and vertebrae (B) of mice bearing the ES‐2 tumour (n = 6–10). Data are expressed as means ± standard deviation. Significance of the differences: ^* P < 0.05, ^** P < 0.01, ^*** P < 0.001 vs. Control.