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. 2018 Aug 15;9:1908. doi: 10.3389/fmicb.2018.01908

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Copyright © 2018 Li, Shen, Zhang, Ying, Zhu, Liu, Xu, Lin, Zhang, Li, Lu, Li, Yi, Bao and Xu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparative genome analyses of several IncA/C group plasmids. Structural comparison of pIA/C-KLUC with those of the most similar IncA/C group plasmids. Circles 1-8 (from outside to inside) are homologous regions of pSRC119-A/C (Accession Number KM670336), pVC1447 (KM083064), unnamed1 (CP017058), R22 (KX8697741), plasmid: 1 (LT882699), pP99-018 (AB277723), pP91278 (AB277724), and pIP1202 (CP000603) compared to pIA/C-KLUC, whereas unmatched regions are left blank. Circles 9 and 11 represent the genes encoded by the forward and reverse strands of pIA/C-KLUC. Circles 12–13 are GC content and GC skew maps of pIA/C-KLUC. The four transfer regions of the plasmid (Tra1-4) are marked in pink in circle 10 and further indicated by arrows. UR-I, II, III, and IV are four large unique regions in pIA/C-KLUC compared with the other plasmids. Classes 1 and 2 represent classes 1 and 2 integrons.