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Housing conditions and experimental design. Exemplary pictures of standard (Control, Ct) and enriched (Environmental Enrichment, EE) housing conditions (A). Mice were housed in groups of 5–6. Enriched cages were equipped with tunnels, houses, and toys. At 4-month-old 5xFAD were randomly allocated to either Ct or EE conditions for 8 weeks. With 6-month-old, mice were tested in behavioral and memory tests followed by euthanasia and tissue collection (B).
