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Global 5-methylated and 5-hydroxymethylated cytosine levels in hippocampus (A). Methyltransferases and Hydroxylases gene expression for Dnmt1, Dnmt3a, Dnmt3b, Tet1 and Tet2 (B). Gene expression levels were determined by real-time PCR. Mean ± Standard Values are mean (SEM) from five independent experiments performed in duplicate are represented; *p < 0.05; **p < 0.01; ***p < 0.001.
