FIGURE 13.

Drug-induced hyperactivity in Taar2-9^−/− mice is not altered. (A) Locomotor activity of Taar2-9^−/− and their wild type (WT) littermates was measured after application of d-AMPH (2.5 mg/kg i.p.) or vehicle (Tween). (B) Cumulated locomotor activity for the 90 min following AMPH treatment. No altered sensitivity was detected comparing the strains. N = 10–14 per group. Data represent mean ± SEM; ^∗∗P < 0.01, one-way ANOVA followed by Tukey’s post hoc test.