FIGURE 7.

Neural activity in odor-naïve Taar2-9^−/− and wild type (WT) littermate mice as assessed by fMRI. Neural activity of odor-naïve Taar2-9^−/− and WT littermate mice was assessed by continuous arterial spin labeling functional magnetic resonance imaging (CASL-fMRI) which reports cerebral perfusion as a proxy for neural activity. Data are means ± SEM (solid lines and shaded area, respectively); N = 11 to 12 per group; differences were tested region-wise for significance using two-way ANOVA. mPFC vp, ventral prelimbic medial prefrontal cortex; mPFC il, ventral infralimbic medial prefrontal cortex; ped Cx, dorsal peduncular cortex; S1, primary somatosensory cortex; S2, secondary somatosensory cortex; M1, primary motor cortex; M2, secondary motor cortex; Cx, cortex; BST, bed nucleus of the stria terminalis; VTA, ventral tegmental area; SN, substantia nigra; Th lat, lateral thalamus; Th med, Medial thalamus; CA1, hippocampal area CA1; Sub, subiculum; DG, dentate gyrus; Sept, septum; PAG dors, dorsal periaqueductal gray; PAG vent, ventral periaqueductal gray; raphe dors, dorsal raphe; raphe med, median raphe; sup colliculi, superior colliculus; hyp lat, lateral hypothalamus; hyp med, medial hypothalamus.