Table 1.

Studies included in the meta-analysis and systematic review with outcomes and follow-up periods

Trials (first author)	Outcomes	Follow-up periods
Araki et al. [7]	Drug-related adverse effects, adverse events leading to drug discontinuation, serious adverse events, death, hypoglycemia, UTIs, genital infections	52 weeks
Ferrannini et al. [8]	Drug-related adverse effects, serious adverse events, adverse events leading to drug discontinuation, hypoglycemia, UTIs, genital infections	78 weeks
Haring et al. [9]	Drug-related adverse effects, adverse events leading to drug discontinuation, serious adverse events, death, hypoglycemia, UTIs, genital infections	24 weeks
Kadowaki et al. [10]	Drug-related adverse effects, adverse events leading to drug discontinuation, serious adverse events, death, hypoglycemia, UTIs, genital infections	52 weeks
Roden et al. [11]	Drug-related adverse effects, adverse events leading to drug discontinuation, serious adverse events, death, hypoglycemia, UTIs, genital infections	24 weeks
Softeland et al. [12]	Drug-related adverse effects, adverse events leading to drug discontinuation, serious adverse events, death, hypoglycemia, UTIs, genital infections	24 weeks
Takkanen et al. [13]	Drug-related adverse effects, adverse events leading to drug discontinuation, serious adverse events, death, hypoglycemia, UTIs, genital infections	12 weeks
Zinman et al. [14]	Drug-related adverse effects, adverse events leading to drug discontinuation, serious adverse events, death, hypoglycemia, UTIs, genital infections	3.1 years

UTIs Urinary tract infections