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. 2018 Mar 5;9(2):449–492. doi: 10.1007/s13300-018-0384-6

Table 9.

Insulin dosing for enteral/parenteral feedings

Adapted from [10]

Situation Basal/nutritional Correctional
Continuous enteral feedings Continue prior basal or, if none, calculate from TDD or consider 5 units NPH/detemir every 12 h or 10 units glargine/degludec daily nutritional: regular insulin every 6 h or rapid-acting insulin every 4 h, starting with 1 unit per 10–15 g of carbohydrate; adjust daily SC regular insulin every 6 h or rapid-acting insulin every 4 h for hyperglycemia
Bolus enteral feedings Continue prior basal or, if none, calculate from TDD or consider 5 units NPH/detemir every 12 h or 10 units glargine/degludec daily nutritional: give regular insulin or rapid-acting insulin SQ before each feeding, starting with 1 unit per 10–15 g of carbohydrate; adjust daily SC regular insulin every 6 h or rapid-acting insulin every 4 h for hyperglycemia
Parenteral feedings Add regular insulin to TPN IV solution, starting with 1 unit per 10 g of carbohydrate; adjust daily SC regular insulin every 6 h or rapid-acting insulin every 4 h for hyperglycemia

IV intravenous, SC subcutaneous, TDD total daily dose, TPN total parenteral nutrition, NPH neutral protamine Hagedorn