Table 4.
Relationship between the re-elevation of HbA1c with teneligliptin 20 mg treatment and various parameters according to logistic regression analysis
| Parameter | Odds ratio (95% CI) | p-value Pr > Chi sq | Partial regression coefficient | R 2 |
|---|---|---|---|---|
| Result of logistic regression analysis (full model) | ||||
| Sex (re-elevation rate for female vs male) | 1.054 (0.535, 2.080) | 0.879 | 0.000 | – |
| Age | 1.014 (0.976, 1.053) | 0.475 | 0.000 | – |
| Duration of DM | 0.970 (0.909, 1.036) | 0.367 | 0.000 | – |
| HbA1c at week 0 | 0.895 (0.552, 1.450) | 0.652 | 0.000 | – |
| HOMA-R at week 0 | 1.097 (0.872, 1.379) | 0.430 | 0.000 | – |
| HOMA-β at week 0 | 1.002 (0.981, 1.024) | 0.836 | 0.000 | – |
| Body weight, ∆ 0–28 weeks | 1.429 (1.164, 1.756) | < 0.001 | 0.196 | – |
| Result of logistic regression analysis (model = stepwise) | ||||
| Body weight, ∆ 0–28 weeks | 1.433 (1.178, 1.744) | < 0.001 | 0.210 | 0.0441 |
CI confidence interval, DM diabetes mellitus, HbA1c glycated hemoglobin, HOMA-β homeostatic model assessment for beta cell function, HOMA-R homeostatic model assessment for insulin resistance, Pr > Chi sq the observed significance probabilities for the Chi square tests, R2 contribution ratio