TABLE 2.
Incremental cardiopulmonary exercise testing on a cycle ergometer (peak exercise data) in patients with chronic hypersensitivity pneumonitis (cHP) and healthy subjects
| cHP | Healthy subjects | p-value | |
| Subjects n | 28 | 18 | |
| Exercise time min | 7.24±3.02 | 7.17±2.05 | 0.89 |
| RER | 1.04±0.14 | 1.08±0.13 | 0.30 |
| Work rate W | 66±35 | 138±69 | <0.001 |
| Work rate % pred | 53±23 | 104±35 | <0.001 |
| V′O2 mL·kg−1·min−1 | 16.6 (12.3–19.98) | 25.1 (16.9–32.0) | 0.003 |
| V′O2 %pred | 83 (63–97) | 112 (89–118) | <0.001 |
| V′E L·min−1 | 50 (42–63) | 71 (45–89) | 0.05 |
| Breathing reserve % MVV | 12 (6.4–34.8) | 41 (32.7–50.8) | <0.001 |
| V′E/V′CO2 slope | 37±5 | 31±4 | <0.001 |
| VT L | 0.91 (0.82–1.25) | 1.75 (1.29–2.21) | <0.001 |
| Respiratory rate breaths·min−1 | 52±11 | 40±10 | 0.001 |
| VT/IC | 0.77±0.15 | 0.68±0.16 | 0.06 |
| ΔPETCO2 mmHg | -0.24±2.67 | -0.11±2.83 | 0.88 |
| HR beats·min−1 | 133±20 | 149±26 | 0.03 |
| HR % pred | 84 (75–89) | 95 (88–99) | 0.008 |
| V′O2/HR mL·beat−1·min−1 | 9.5±2.9 | 12.6±5.0 | 0.01 |
| V′O2/HR % pred | 93±19 | 122±29 | <0.001 |
| SpO2 % | 81±7 | 95±2 | <0.001 |
| Borg dyspnoea score | 8 (5–10) | 4 (1–7) | 0.004 |
| Borg leg discomfort score | 8 (4–9) | 7 (4–9) | 0.71 |
| ΔIC from rest L | -0.01±0.20 | 0.11±0.25 | 0.08 |
| ΔIC from rest % | 1.92±12 | 4.96±11 | 0.43 |
Data are presented as mean±sd or median (25th–75th percentile), unless otherwise stated. RER: respiratory exchange rate; V′O2: oxygen production; V′E: minute ventilation; MVV: maximal voluntary ventilation; V′CO2: carbon dioxide production; VT: tidal volume; IC: inspiratory capacity; PETCO2: end-tidal carbon dioxide tension; HR: heart rate; SpO2: arterial oxygen saturation measured by pulse oximetry.