Table 2.
Associations of patient characteristics and time to treatment.
| Patient Characteristic (N = 177) | Mean Difference,a days (95% CI) |
|---|---|
| Age (> 70/≤70) | −10.2 (−25.3, 4.99) |
| Sex (F/M) | −3.06 (−32.5, 26.43) |
| Race (Nonwhite/White) | 20.9 (−3.50, 45.2) |
| Symptomatic (N/Y) | −2.66 (−15.2, 9.83) |
| ECOG (≥ 2/< 2) | −5.46 (−21.2, 10.2) |
| Family history (N/Y) | 6.06 (−12.9, 25.0) |
| Pack years (> 30/≤30) | −4.45 (−18.9, 10.0) |
| DM (N/Y) | 5.01 (−10.2, 20.2) |
| CKD (N/Y) | 2.80 (−18.0, 23.6) |
| COPD (N/Y) | −3.25 (−16.5, 9.98) |
| Any respiratory comorbidity (N/Y) | −9.24 (−23.5, 4.98) |
| CAD (N/Y) | 6.69 (−23.7, 2.76) |
| Any CVD comorbidity (N/Y) | 3.94 (−10.6, 18.4) |
| Other cancer history (N/Y) | −17.4 (−34.4, −0.47) |
| Alcohol dependence (N/Y) | −25.8 (−66.2, 14.6) |
| SCS > 9 (N/Y) | −13.6 (−26.9, −0.25) |
| Any psychiatric illness (N/Y) | 8.43 (−1.97, 18.8) |
| Ventilatory defect (N/Y) | |
| Obstructive | −4.06 (−16.8, 8.68) |
| Restrictive | 4.29 (−23.6, 32.2) |
| DLCO limitation | −0.53 (−12.8, 11.7) |
| Tumor size < 2 cm | −3.34 (−16.0, 9.30) |
| SCLC (N/Y) | 13.2 (6.45, 58.6) |
| Stage I (N/Y) | −13.7 (−26.8, −0.62) |
| Treatment categoryb | |
| Surgery vs. SBRT/XRT | −17.8 (−34.7, −0.86) |
| Surgery vs. chemoradiation | 8.95 (−1.93, 19.8) |
| SBRT/XRT vs. Chemoradiation | 26.7 (10.4, 43.1) |
CAD = coronary artery disease; CI = confidence interval; CKD = chronic kidney disease; COPD = chronic obstructive pulmonary disease; CTB = chest tumor board; CVD = cardiovascular disease; DLCO = diffusion capacity of the lung for carbon monoxide; DM = diabetes mellitus; ECOG PS = Eastern Cooperative Oncology Group Performance Status; FEV1 = forced expiratory volume in 1 s; SBRT = stereotactic body radiotherapy; SCLC = small cell lung cancer; SCS = simplified comorbidity score; TLC = total lung capacity; XRT = radiotherapy.
Bolded variables: statistically significant, p < 0.05.
Independent-samples tests (t-test for equality of means and Levene’s test for equality of variances).
Independent-samples Kruskal-Wallis test for nonparametric distribution, p < 0.001.