Table 3.
Pathogenic Oral Bacteria Found in Colitis Rodent and Human Models. Polybacterial infection was performed in mice as described in our publication (16). We analyzed the BLAST results – pathogenic oral bacteria were characterized and classified using published literature. Our preliminary data show that polybacterial infection alters the colon microbiome, and modulates the amount of healthy oral and healthy gut bacteria in the distal colon.
| Bacteria Genus | Function Related to Colitis | 
|---|---|
| Eubacterium | Certain species, such as Eubacterium rectale is found predominately in self-limiting colitis (60) | 
| Prevotella | Invades terminal ileum and colon of patients with ulcerative colitis (61) | 
| Bacteriodes | Commensal Bacteriodes induce colitis in host (62) | 
| Fusobacterium | The species Fusobacterium nucleatum may correlate with IBS (63) | 
| Mesorhizobium | Prevalent in those with Crohn’s disease (64) |