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. 2018 Aug 22;8:135. doi: 10.1186/s13568-018-0667-3

Table 3.

ANOVA for Box–Behnken design

Source Sum of squares df Mean square F value p-value prob > F
Model 5.562E+007 9 6.180E+006 73.81 < 0.0001
A-T 4.735E+007 1 4.735E+007 565.51 < 0.0001
B-DO 48615.39 1 48615.39 0.58 0.4710
C-IPTG 2.827E+005 1 2.827E+005 3.38 0.1088
AB 4.387E+005 1 4.387E+005 5.24 0.0559
AC 45926.63 1 45926.63 0.55 0.4830
BC 1900.39 1 1900.39 0.023 0.8845
A2 4.177E+006 1 4.177E+006 49.88 0.0002
B2 8.466E+005 1 8.466E+005 10.11 0.0155
C2 1.741E+006 1 1.741E+006 20.80 0.0026
Residual 5.862E+005 7 83736.38
 Lack of fit 3.009E+005 3 1.003E+005 1.41 0.3637
 Pure error 2.853E+005 4 71316.17
Cor total 5.621E+007 16 Square