Table 3.
Cut-off values of MR parameters (% change in tCho, ADC and volume) to differentiate pathological and clinical responders and non-responders using ROC analysis.
| Time points | tCho (mm/Kg) | ADC (10−3 mm2/s) | Volume (cm3) |
|---|---|---|---|
| CUT-OFF VALUES TO DIFFERENTIATE PATHOLOGICAL RESPONDERS AND NON-RESPONDERS | |||
| Tp1 | Cut-off (−39.43%) (Sens: 66.7%; Spec: 63.6%; AUC: 0.54) |
Cut-off (13.19%) (Sens: 50%; Spec: 50%; AUC: 0.49) |
Cut-off (−21.33%) (Sens: 53.8%; Spec: 50%; AUC: 0.52) |
| Tp3 | Cut-off (−73.13%) (Sens: 70.6%; Spec: 66.7%; AUC: 0.76) |
Cut-off (28.32%) (Sens: 66.7%; Spec: 64.7%; AUC: 0.69) |
Cut-off (−64.53%) (Sens: 70.6%; Spec: 66.7%; AUC: 0.68) |
| CUT-OFF VALUES TO DIFFERENTIATE CLINICAL RESPONDERS (Cr) AND NON-RESPONDERS (CNR) | |||
| Tp1 | Cut-off (−39.80%) (Sens: 55.6%; Spec: 52%; AUC: 0.52) |
Cut-off (10.72%) (Sens: 92%; Spec: 90%; AUC: 0.89) |
Cut-off (−16.49%) (Sens: 60%; Spec: 68%; AUC: 0.69) |
| Tp3 | Cut-off (−70.51%) (Sens: 80%; Spec: 76.9%; AUC: 0.88) |
Cut-off (25.50%) (Sens: 88.5%; Spec: 100%; AUC: 0.97) |
Cut-off (−56.83%) (Sens: 93.3%; Spec: 88.5%; AUC: 0.97) |
AUC, Area under the curve; Sens, sensitivity; Spec, specificity.