Table 1.
Obstetrical and clinical characteristics of women with SSc quantified for male DNA and soluble HLA-G (sHLA-G) levels.
| SSc women | Age at blood draw (years) | Disease duration at blood draw (years) | # of sons | Age of last son (years) | Spontaneous or induced abortions | Blood transfusions | # of older brothers | Male Mca (gEq/M) | sHLA-Gb (IU) |
|---|---|---|---|---|---|---|---|---|---|
| SSc01 | 63 | 10 | 1 | 25 | 1 | Uknc | 0 | 22.5d | 84.0 |
| SSc02 | 60 | 5 | 1 | 35 | 0 | 0 | 0 | 0.5 | 23.6 |
| SSc03 | 45 | 2 | 1 | 20 | 0 | 0 | 0 | 12.7 | 17.1 |
| SSc04 | 58 | 1 | 1 | 30 | 0 | 0 | 1 | 1.6 | 49.2 |
| SSc05 | 73 | 6 | 2 | Ukn | 0 | 0 | 0 | 0 | 119.7 |
| SSc06 | 49 | 5 | 1 | 9 | 1 | 0 | 0 | 4.5 | 83.5 |
| SSc07 | 78 | 23 | 1 | 56 | 0 | 0 | 0 | 2.6 | 83.0 |
| SSc08 | 64 | 1 | 6 | Ukn | 0 | 0 | 1 | 0.0 | 62.2 |
| SSc09 | 55 | 6 | 3 | 33 | 0 | 1e | 0 | 12.5 | 25.2 |
| SSc10 | 45 | 5 | 2 | Ukn | 1 | 0 | 3 | 10.0 | 21.3 |
| SSc11 | 51 | 4 | 2 | 15 | 1 | 0 | 1 | 4.3 | 19.0 |
| SSc12 | 60 | 9 | 1 | 36 | 0 | 0 | 1 | 2.7 | 116.9 |
| SSc13 | 62 | 6 | 1 | 37 | 0 | 0 | 1 | 0.0 | 52.8 |
| SSc14 | 47 | 18 | 1 | 16 | 0 | 0 | 0 | 14.0 | 90.8 |
| SSc15 | 50 | 5 | 2 | 17 | 0 | 0 | 1 | 0.0 | 61.3 |
| SSc16 | 58 | 5 | 2 | 33 | 0 | 4 | 0 | 4.5 | 66.2 |
| SSc17 | 66 | 9 | 1 | 37 | 3 | 0 | 1 | 0.0 | 31.0 |
| SSc18 | 53 | 3 | 1 | 19 | 1 | 0 | 1 | 0.0 | 142.0 |
| SSc19 | 62 | 23 | 1 | Ukn | 1 | 0 | 0 | 0.0 | 95.9 |
| SSc20 | 72 | 6 | 1 | Ukn | 2 | Ukn | 2 | 0.0 | 177.2 |
| SSc21 | 64 | 5 | 2 | Ukn | 0 | 1 | 1 | 0.0 | 176.7 |
| SSc22 | 35 | 5 | 1 | 10 | 0 | 0 | 2 | 0.0 | 123.9 |
| SSc23 | 48 | 0 | 2 | 20 | 0 | 0 | 3 | 0.0 | 87.9 |
| SSc24 | 43 | 2 | 2 | Ukn | 1 | 1 | 0 | 0.0 | 98.9 |
| SSc25 | 57 | 9 | 2 | Ukn | 5 | 1 | 3 | 0.0 | 54.2 |
| SSc26 | 49 | 12 | 1 | 44 | Ukn | 0 | Ukn | 9.7 | 25.9 |
| SSc27 | 40 | 13 | 1 | 15 | 2 | 0 | 0 | 0.0 | 47.1 |
| SSc28 | 66 | 16 | 2 | 37 | 0 | 0 | 2 | 0.0 | 34.5 |
| SSc29 | 62 | 13 | 1 | 40 | 2 | Ukn | 0 | 2.3 | 67.5 |
| SSc30 | 61 | 1 | 1 | 32 | 1 | 0 | 1 | 7.1 | 16.3 |
| SSc31 | 52 | 2 | 1 | 32 | 0 | 0 | 1 | 0.0 | 64.2 |
| SSc32 | 45 | 22 | 1 | 24 | 0 | 0 | 1 | 0.0 | 89.2 |
| SSc33 | 37 | 0 | 1 | 7 | 0 | 0 | 1 | 0.0 | 164.0 |
| SSc34 | 54 | 17 | 1 | 26 | 0 | 0 | 0 | 0.0 | 76.3 |
| SSc35 | 56 | 12 | 1 | 17 | 1 | 0 | 0 | 53.2 | 49.8 |
| SSc36 | 40 | 3 | 1 | 15 | 1 | 0 | 2 | 0.0 | 92.8 |
| SSc37 | 53 | 19 | 2 | 25 | 2 | 0 | 0 | 0.5 | 37.5 |
| SSc38 | 75 | 25 | 4 | 33 | 1 | 2 | 0 | 0.0 | 106.3 |
aMale microchimerism is expressed in genome equivalent of male cells per million of maternal cells (gEq/M).
bQuantities of sHLA-G are expressed in International Units per mL of plasma (IU/mL).
cUnknown data are abbreviated with ukn.
dPositive values for male Mc are in bold.
eWomen who had an history of transfusion are in bold and were excluded from statistical analysis, as well as women with unknown data for blood transfusion.