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Corrigendum to “Branched chain amino acids attenuate major pathologies in mouse models of retinal degeneration and glaucoma” [Heliyon 4(2) (March 2018) e00544]
aDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto, 606-8507, Japan
bDepartment of Experimental Therapeutics, Institute for Advancement of Clinical and Translational Science, Kyoto University Hospital, Sakyo-ku, Kyoto, 606-8507, Japan
aDepartment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto, 606-8507, Japan
bDepartment of Experimental Therapeutics, Institute for Advancement of Clinical and Translational Science, Kyoto University Hospital, Sakyo-ku, Kyoto, 606-8507, Japan
cCenter for Anatomical Studies, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto, 606-8501, Japan
dLaboratory of Functional Biology, Kyoto University Graduate School of Biostudies, Sakyo-ku, Kyoto, 606-8501, Japan
The data presented in the original Supplemental Figure 3 were incorrectly calculated. The data were described as amino acid concentration divided by tissue weight, however the figure displayed non-normalized amino acid concentrations. The authors apologize for the mistake. A corrected Supplemental Figure 3 and figure legend are displayed below. This correction does not, in any way, compromise the findings of the study, either in terms of the methodology, results, or interpretations drawn from the data therein.
Additional information
No additional information is available for this paper.
The following is the supplementary data related to this article:
BCAA_spl__spl__spl_Figure S3 170519submit
Figure S3. Concentration of BCAAs in eyes increased in a dose-dependent manner. Related to Materials & Methods. BCAA concentrations in eyeballs were measured 2 hours after a single administration of BCAAs (the doses for intraperetonial injection were 0, 0.375, 0.75, or 1.5 g/kg; the dose for oral administration was 0.75 g/kg). Eyeballs of 2-month-old wild-type mice were enucleated after pentobarbital overdose. Immediately after enucleation, eyeballs were weighed and then frozen. Concentration of (A) leucine (Leu), (B) isoleucine (Ile), and (C) valine (Val) were measured at Ajinomoto Co. using a UF-Amino Station system. Key: C, no administration control; Peritoneal, intraperitoneal administration of BCAAs; Oral, oral administration of BCAAs. *p < 0.05, unpaired t-test, vs. no administration control.
This section collects any data citations, data availability statements, or supplementary materials included in this article.
Supplementary Materials
BCAA_spl__spl__spl_Figure S3 170519submit
Figure S3. Concentration of BCAAs in eyes increased in a dose-dependent manner. Related to Materials & Methods. BCAA concentrations in eyeballs were measured 2 hours after a single administration of BCAAs (the doses for intraperetonial injection were 0, 0.375, 0.75, or 1.5 g/kg; the dose for oral administration was 0.75 g/kg). Eyeballs of 2-month-old wild-type mice were enucleated after pentobarbital overdose. Immediately after enucleation, eyeballs were weighed and then frozen. Concentration of (A) leucine (Leu), (B) isoleucine (Ile), and (C) valine (Val) were measured at Ajinomoto Co. using a UF-Amino Station system. Key: C, no administration control; Peritoneal, intraperitoneal administration of BCAAs; Oral, oral administration of BCAAs. *p < 0.05, unpaired t-test, vs. no administration control.