Table 1.
The demographic and clinical characteristics of the study cohort.
| Items | Rheumatoid arthritis patients | Healthy controls |
|---|---|---|
| N | 59 | 46 |
| Age, yr | 50.4±14.7 | 44.7±13.7 |
| Female, n (%) | 52 (91.3) | 29 (89.3) |
| Male, n (%) | 7 (8.7) | 17 (10.7) |
| CRP, mg/L | 40.2±45.0 | – |
| ESR, mm/h | 54.8±28.7 | – |
| HAQ | 1.1±0.6 | – |
| DAS28 | 4.8±1.0 | – |
| WBCs (×109/L) | 8.1±2.9# | 6.1±1.1 |
| Lymphocytes, %* | 15.9±6.6# | 23.2±6.8 |
| IL-37 (ng/L) | 139.5±57.76# | 114.2±22.47 |
| TNF-α (ng/L) | 4.84±1.64# | 3.62±0.83 |
| IL-6 (ng/L) | 9.07±13.35# | 0.74±0.58 |
CRP – c-reactive protein; ESR – erythrocyte sedimentation rate; HAQ – Health Assessment Questionnaire; DAS28 – Disease Activity Score-28; SDAI – Simplified Disease Activity Index; CDAI – Clinical Disease Activity Index; WBCs – white blood counts; IL – interleukin; TNF-α – tumor necrosis factor-α. Values are shown as mean ±SD, unless otherwise noted.
*
Percentage of total white blood cells in peripheral blood.
#
p<0.05 compared to healthy controls.