Table 1.

SNPs, MAF and test for HWE and corresponding reported MAF in the 1000 genomes project in South Asian and European populations

Chromosome	Gene	SNP	Major/minor alleles	HWE*	MAF†	MAF EUR‡	MAF SAS§
1	Y402H	rs1061170	T/C	0.6854	0.323	0.362	0.287
4	TLR3	rs3775291	C/T	0.9347	0.235	0.324	0.263
6	C2	rs547154	C/A	0.3813	0.187	0.089	0.156
6	SKIV2L	rs438999	A/G	0.6932	0.183	0.089	0.148
6	LOC107986598¶	rs4711751	T/C	1	0.423	0.487	0.330
6	FRK	rs1999930	C/T	0.3957	0.075	0.281	0.052
9	ABCA1	rs1883025	C/T	0.0797	0.432	0.240	0.413
10	ARMS2	rs10490923	G/A	0.7299	0.149	0.130	0.148
10	ARMS2	rs10490924	G/T	0.1953	0.319	0.195	0.343
10	HTRA1	rs2672598	T/C**	0.2969	0.524	0.499	0.464
15	LIPC	rs10468017	C/T	0.9195	0.176	0.283	0.184
16	CETP	rs3764261	C/A	0.0737	0.295	0.292	0.321
19	APOE	rs429358	T/C	1	0.097	0.155	0.087
19	APOE	rs7412	C/T	0.5232	0.050	0.063	0.044
19	CFD	rs3826945	T/C	0.8424	0.344	0.313	0.334

*P value for tests for departure from Hardy-Weinberg equilibrium (HWE) in controls.

†Minor allele frequency (MAF) in controls.

‡MAF from 1000 genome study for European ancestry available at https://www.ncbi.nlm.nih.gov/snp.

§MAF from 1000 genome study for South Asian ancestry available at https://www.ncbi.nlm.nih.gov/snp.

¶SNP located near VEGFA.

**Minor allele considered as C for comparison with other studies.

SNP, single nucleotide polymorphisms.